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CAS NO.875781-17-2
Hot sale 875781-17-2 Top quality 5-Bromo-1H-pyrazolo[3,4-b]pyridine manufacturer
5-bromo-1H-pyrazolo [3,4-B] pyridine Chinese alias 5-bromopyrazolo [3,4-b] pyridine, pyrazolo [3,4-B] pyridine compound is a very important kind of thick heterocyclic ring, due to its specific physiological activity and structural similarity with indole, azafindole, etc., it has aroused widespread interest and is a very important type of dense heterocyclic compound. They have good curative effects in the prevention and treatment of gram-negative and positive bacteria, tumors and cancers, asthma, neurological diseases, osteoporosis and Alzheimer's disease, and have a wide range of applications in the fields of pharmaceuticals, pesticides and dyes.
When synthesizing pyrazolopyridine compounds with pyridine ring as the parent ring, hydrazine or substituted hydrazine is generally used to close the ring. If 3, 6-dichloro-2-pyridine formaldehyde reacts with hydrazine to undergo bromination reaction, 5-bromo-1H-pyrazolo [3,4-B] pyridine can be prepared. In addition, 5-bromo-1H-pyrazolo [3,4-b] pyridine can be synthesized from 2-fluoro -5-bromopyridine -3-formaldehyde in a yield of about 46%; or 5-bromo-1H-pyrazolo [3,4-b] pyridine can be synthesized from 3-aminopyrazole and 2-bromomalondialdehyde in a yield of about 11%; in this paper, 5-bromo-2-hydrazinylpyridine hydrochloride is used as the starting material to prepare 5-bromo-1H-pyrazolo [3,4-B] pyridine by intramolecular ring-forming reaction. The preparation reaction formula is as follows. Fig. 1 5-bromo-1H-pyrazolo [3,4-B] pyridine preparation reaction formula
Established in 2010, located in Hangzhou Qinglan science park, lingruichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals tovarious industries.n our R&D centre. we have a staff of skilled and experienced research chemists. This has enabled us to meet the special reauirements of our customers and it has enabled us to provide quality products at competitive prices.
1. How can we guarantee quality
Always a pre-production sample before mass production;
Always final Inspection before shipment;
2.What can you buy from us
Plant Extracts,Cosmetics Raw Materials,Vitamin Raw Materials,Pharmaceutical Raw Materials and Intermediates
3. Why should you buy from us not from other suppliers
Our company mainly devoted in producing pharmacetical intermediates , Vitamins , and health supplement , the quality and technical content can reach the advance level in China .Our products are sold well in China as well as in more than 20 countries.
Lingrui's credo is committed to your reliable business partner,reliable quality, competitive prices and superior service, lf you are interested in any of our products or would like to discuss a custom order, please feel free to contact us. We are looking forward to forming successful business relationships with new clients around the world in the near future !