Keywords

• High purity 763114-26-7
• low price 763114-26-7
• 763114-26-7 good supplier

Quick Details

• ProName: High purity 763114-26-7 low price 2-fl...
• CasNo: 763114-26-7
• Molecular Formula: C16H11FN2O3
• Application: 5-[(3, 4-dihydro-4-oxo-1-phthalazinyl)...
• DeliveryTime: Stocks
• PackAge: according to customers' requirements
• Port: Any port
• ProductionCapacity: 100 Metric Ton/Day
• Purity: 99%
• Storage: Sealed in dry,Room Temperature
• Transportation: By air(EMS or EUB or FedEx or TNT ect....
• LimitNum: 1 Gram

Superiority

High purity 763114-26-7 low price 2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)benzoic acid good supplier

5-[(3, 4-dihydro-4-oxo-1-phthalazinyl) methyl]-2-fluorobenzoic acid is an intermediate in organic synthesis and pharmaceutical intermediates, mainly used in laboratory research and development process and biochemical production process.

preparation of compound 3: add sodium formate (1G, 0.018mol) and methanol (16ml) to a round bottom flask, after stirring and cooling to 0 ℃, dimethyl phosphite (2.1ml,0.022mol) was added dropwise. After dropping, O-carboxybenzaldehyde (2.2g,0.014mol) was slowly added within 15min, the reaction was allowed to warm to room temperature for 4H, then methanesulfonic acid (1.3ml,0.019mol) was added dropwise over 10min and stirred, and concentrated to dryness under reduced pressure. Water (20ml) was added, After extraction with dichloromethane, the dichloromethane layer was collected and dried over anhydrous Na2SO4. After filtration and concentration under reduced pressure, a white solid (2.6g, 91% yield) was obtained. Preparation of compound 4, namely 5-[(3, 4-dihydro-4-oxo-1-phthalazinyl) methyl]-2-fluorobenzoic acid: compound 3(2.6g,0.011mol) and 2-fluoro-5-formylbenzoic acid (2.1g,0.012mol) were dissolved in anhydrous tetrahydrofuran (25ml) and cooled to 0 °c, slowly Dropwise add triethylamine (1.0ml,0.007mol), after dropping to room temperature reaction 5H, then slowly raise the temperature to 70 ℃, add hydrazine hydrate (5.1ml, 0.107mol) reaction 3H, down to room temperature, adding an appropriate amount of hydrochloric acid (2mol/L) to adjust the PH to acidic, no longer precipitated solid. The product was filtered with suction, washed with water and ethyl acetate, and dried to give a yellow solid (1.9g, 83% yield).

Details

Established in 2010, located in Hangzhou Qinglan science park, lingruichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals tovarious industries.n our R&D centre. we have a staff of skilled and experienced research chemists. This has enabled us to meet the special reauirements of our customers and it has enabled us to provide quality products at competitive prices.

1. How can we guarantee quality

Always a pre-production sample before mass production;

Always final Inspection before shipment; 

2.What can you buy from us

Plant Extracts,Cosmetics Raw Materials,Vitamin Raw Materials,Pharmaceutical Raw Materials and Intermediates

3. Why should you buy from us not from other suppliers

Our company mainly devoted in producing pharmacetical intermediates , Vitamins , and health supplement , the quality and technical content can reach the advance level in China .Our products are sold well in China as well as in more than 20 countries.

Lingrui's credo is committed to your reliable business partner,reliable quality, competitive prices and superior service, lf you are interested in any of our products or would like to discuss a custom order, please feel free to contact us. We are looking forward to forming successful business relationships with new clients around the world in the near future !