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CAS NO.632-46-2
Direct Manufacturer 2,6-Dimethylbenzoic acid 632-46-2 in bulk supply
2,6-dimethylbenzoic acid is a white solid powder under normal temperature and pressure. During the organic synthesis and conversion, the carboxyl group in 2,6-dimethylbenzoic acid can be converted into hydroxyl group under the Chemalbook reduction of lithium tetrahydroaluminate or borane, and can also be converted into corresponding amide products through amine ester exchange reaction. In addition, the carboxyl group can also generate corresponding anhydride products through dehydration and condensation reaction.
At room temperature, mix 2,6-dimethylphenylboronic acid (150mg), KOMe (2.0 equivalent) and catalyst [(IPr) CuCl] (14.4mg, 3.0mol%) in nitrogen atmosphere for 5-10 minutes, and fill the reaction tube with carbon dioxide by applying 4-5 cycles of vacuum pumping and CO2 filling. Seal the reaction tube, then stir the reaction at 70 ° C for 24 Chemicalbook hours, then carefully add 2.0M hydrochloric acid aqueous solution to quench the reaction mixture. Dilute the reaction mixture with water, extract the reaction mixture with ethyl acetate three times, and wash the combined organic phase with salt water. Dry the organic phase on anhydrous sodium sulfate, filter the combined organic phase, remove the solvent under reduced pressure, and separate and purify the product by silica gel column chromatography to obtain the target product, 2,6-dimethylbenzoic acid.
Established in 2010, located in Hangzhou Qinglan science park, lingruichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals tovarious industries.n our R&D centre. we have a staff of skilled and experienced research chemists. This has enabled us to meet the special reauirements of our customers and it has enabled us to provide quality products at competitive prices.
1. How can we guarantee quality
Always a pre-production sample before mass production;
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2.What can you buy from us
Plant Extracts,Cosmetics Raw Materials,Vitamin Raw Materials,Pharmaceutical Raw Materials and Intermediates
3. Why should you buy from us not from other suppliers
Our company mainly devoted in producing pharmacetical intermediates , Vitamins , and health supplement , the quality and technical content can reach the advance level in China .Our products are sold well in China as well as in more than 20 countries.
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