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CAS NO.5397-03-5
High purity 5397-03-5 low price methyldithiocarbazate factory
methyl hydrazine dithioformate is a pharmaceutical intermediate, which can be prepared by reacting hydrazine hydrate, carbon disulfide and dimethyl sulfate. It has been reported that it can be used to prepare a kind of amine thiourea anticancer drug.
Add 60ml of water and 50ml of isopropanol in a ML three-neck flask, and cool in a water bath, add 49.5g(0.75mol) potassium hydroxide in portions, stir to make it fully soluble, slowly add 39g(0.75mol)85% hydrazine monohydrate at ≤ 20 ℃, add it in 10 minutes, remove the water bath for ice bath, Dropwise add ice-cold 100g (57.5 mol) carbon disulfide at 10 °c for 0.75 minutes, add mixed 2 hours, and then raise the temperature to 15 °c, ice-cold 94 was added dropwise over 2.5 hours. 5G (0.75mol) dimethyl sulfate, after adding, and then continue to stir 1 hours. The resultant white precipitate was filtered, rinsed with a small amount of ice water, dried in vacuo, and recrystallized from dichloromethane to give 55g of colorless flaky crystals in a yield of 60% at mp.81 -82 °c.
Established in 2010, located in Hangzhou Qinglan science park, lingruichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals tovarious industries.n our R&D centre. we have a staff of skilled and experienced research chemists. This has enabled us to meet the special reauirements of our customers and it has enabled us to provide quality products at competitive prices.
1. How can we guarantee quality
Always a pre-production sample before mass production;
Always final Inspection before shipment;
2.What can you buy from us
Plant Extracts,Cosmetics Raw Materials,Vitamin Raw Materials,Pharmaceutical Raw Materials and Intermediates
3. Why should you buy from us not from other suppliers
Our company mainly devoted in producing pharmacetical intermediates , Vitamins , and health supplement , the quality and technical content can reach the advance level in China .Our products are sold well in China as well as in more than 20 countries.
Lingrui's credo is committed to your reliable business partner,reliable quality, competitive prices and superior service, lf you are interested in any of our products or would like to discuss a custom order, please feel free to contact us. We are looking forward to forming successful business relationships with new clients around the world in the near future !