Keywords

• High quality 38078-09-0
• 38078-09-0 factory
• 38078-09-0 in China

Quick Details

• ProName: High quality 38078-09-0 Diethylaminosu...
• CasNo: 38078-09-0
• Molecular Formula: C4H10F3NS
• Appearance: Colorless to Yellow to Orange liquid
• Application: Diethylamino sulfur trifluoride (DAST)...
• DeliveryTime: Stocks
• PackAge: according to customers' requirements
• Port: Any port
• ProductionCapacity: 100 Metric Ton/Day
• Purity: 95%
• Storage: 2-8°C
• Transportation: By air(EMS or EUB or FedEx or TNT ect....
• LimitNum: 1 Gram

Superiority

High quality 38078-09-0 Diethylaminosulfur trifluoride factory in China

Diethylamino sulfur trifluoride, commonly used abbreviation DAST, is a fluorination reagent widely used in organic synthesis. It is (dihydrocarbyl amino) A member of the sulfur trifluoride family. DAST is a nucleophilic fluorination reagent, which can convert hydroxyl compounds into monofluorinated compounds, aldehydes and ketones into difluorinated compounds, but has no effect on the carbonyl groups of carboxylic acids and their derivatives. DAST is a liquid. It can be stored for a long time at room temperature or in a refrigerator under dry conditions. DAST will decompose at 90°C, and improper handling will cause the risk of explosion. However, due to its simple operation and strong versatility, DAST is one of the most widely used fluorinated reagents. (edited by ChemicalBook Yuxin)

The reaction of DAST to convert primary alcohols into corresponding fluorides can be carried out under very mild conditions. Usually, the material is added at-78oC to inhibit the initial exothermic process, and then the reaction is automatically raised to room temperature for a moment (Formula 1). Although the reaction of secondary alcohol is also fed at -78 oC, in order to promote the reaction, it is generally necessary to raise the temperature or reflux in CH2Cl2 for a long time (formula 2, formula 3). In most cases, the yield of fluorinated products is moderate, but the reaction has a high chemical selectivity and is suitable for selective fluorination of polyfunctional molecules.
Under almost the same conditions as the fluorination of alcohol, DAST can convert aldehydes and ketones into corresponding difluorides. In contrast, their reaction temperature is higher than that of alcohol; the reaction conditions of aldehydes are milder than ketones. For example, after the aldehyde is treated with DAST at low temperature or room temperature, the corresponding difluoride (formula 4, formula 5) can be obtained. However, the ketone needs to be co-heated with DAST for a long time to generate the corresponding difluoride (formula 6).

Details

Established in 2010, located in Hangzhou Qinglan science park, lingruichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals tovarious industries.n our R&D centre. we have a staff of skilled and experienced research chemists. This has enabled us to meet the special reauirements of our customers and it has enabled us to provide quality products at competitive prices.

1. How can we guarantee quality

Always a pre-production sample before mass production;

Always final Inspection before shipment; 

2.What can you buy from us

Plant Extracts,Cosmetics Raw Materials,Vitamin Raw Materials,Pharmaceutical Raw Materials and Intermediates

3. Why should you buy from us not from other suppliers

Our company mainly devoted in producing pharmacetical intermediates , Vitamins , and health supplement , the quality and technical content can reach the advance level in China .Our products are sold well in China as well as in more than 20 countries.

Lingrui's credo is committed to your reliable business partner,reliable quality, competitive prices and superior service, lf you are interested in any of our products or would like to discuss a custom order, please feel free to contact us. We are looking forward to forming successful business relationships with new clients around the world in the near future !