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Tel: 86 571-88092529
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Tel: 86 571-88092529
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URL: http://www.lingruichem.com
Province/state: Zhejiang
City: Hangzhou
Street: 201-B 2# Building Qinglan science park, 321# JinPeng Str. Xihu District Hangzhou City, PR.CHINA
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CAS NO.27876-94-4
Supply Competitive price 27876-94-4 High quality Crocetin
overview
Fanhong [flower] acid is also known as saffron acid. Crocin acid is a kind of water-soluble carotenoid that coexists in saffron and gardenia, which is rare in nature. It is the main component of saffron. It has the functions of anti-cancer, tumor inhibition, blood lipid reduction, liver protection, quenching free radicals, anti-oxidation, etc. In addition, it also has the advantages of good water solubility, strong coloring power, stable to light, bright golden yellow in the range of pH = 1~4, once the coloring is very stable, etc, it is widely used in the fields of medicine and food.
biological activity
Transcrocetin extracted from saffron (Crocus sativus L.) is a high-affinity NMDA receptor antagonist that can penetrate the blood-brain barrier.
Target
Human Endogenous Metabolite
in vitro studies
Transcrocetin (trans-Crocetin), a saffron metabolite originating from the crocin apocarotenoids, has been shown to exert strong NMDA receptor affinity and is thought to be responsible for the CNS activity of saffron.To ensure unchanged viability of Caco-2 cells throughout the transport experiments, cellular mitochondrial dehydrogenase activity of Caco-2 cells is measured by MTT assay after a 24 h incubation period with the test compounds: Hydroalcoholic saffron extract saffron extract (SE, 0.5-1 mg/mL) and crocin-1 (250-1000 µM) reveal no negative significant changes in cellular viability. Transcrocetin at 10 µM level does not change viability while higher concentrations (40-160 µM) reduces significantly cellular viability.
Established in 2010, located in Hangzhou Qinglan science park, lingruichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals tovarious industries.n our R&D centre. we have a staff of skilled and experienced research chemists. This has enabled us to meet the special reauirements of our customers and it has enabled us to provide quality products at competitive prices.
1. How can we guarantee quality
Always a pre-production sample before mass production;
Always final Inspection before shipment;
2.What can you buy from us
Plant Extracts,Cosmetics Raw Materials,Vitamin Raw Materials,Pharmaceutical Raw Materials and Intermediates
3. Why should you buy from us not from other suppliers
Our company mainly devoted in producing pharmacetical intermediates , Vitamins , and health supplement , the quality and technical content can reach the advance level in China .Our products are sold well in China as well as in more than 20 countries.
Lingrui's credo is committed to your reliable business partner,reliable quality, competitive prices and superior service, lf you are interested in any of our products or would like to discuss a custom order, please feel free to contact us. We are looking forward to forming successful business relationships with new clients around the world in the near future !