Keywords

• High purity Best price 16037-91-5
• 16037-91-5 exporter Competitive price
• lowest price Sodium Stibogluconate

Quick Details

• ProName: High purity Best price 16037-91-5 Sodi...
• CasNo: 16037-91-5
• Molecular Formula: C12H37Na3O27Sb2
• Appearance: solid
• Application: Anti-kala-azar drugs
• DeliveryTime: Stocks
• PackAge: according to customers' requirements
• Port: Any port
• ProductionCapacity: 100 Metric Ton/Day
• Purity: 99%
• Storage: 2-8°C
• Transportation: By air(EMS or EUB or FedEx or TNT ect....
• LimitNum: 1 Gram

Superiority

High purity Best price 16037-91-5 Sodium Stibogluconate exporter Competitive price

Sodium stibogluconate (SSG, Stibogluconate trisodium nonahydrate, Lenocta, VQD-001) is a pentavalent antimony derivative, which is an effective and selective inhibitor of protein tyrosine phosphatase (PTPase). Sodium stibogluconate inhibited the activity of Src homology 2 domain-containing phosphatase 1 (SHP-1) and SHP-2 in 99% at a concentration of 10 μg/ml, while the drug concentration required to produce a similar degree of inhibition on PTP1B was 100 μg/ml. Sodium stibogluconate is also a drug used to treat leishmaniasis.

Sodiumstibogluconate(Stibogluconatetrisodiumnonahydrate)inhibits99%ofSHP-1activityat10μg/mL,atherapeuticconcentrationofthedrugforleishmaniasis.SimilardegreesofinhibitionofSHP-2andPTP1Brequired100μg/mLSodiumstibogluconate.TheinhibitionofcellularPTPasesbytheSodiumstibogluconateissuggestedbyitsrapidinductionoChemicalbookftyrosinephosphorylationofcellularproteinsinBaf3cellsanditsaugmentationofIL-3-inducedJanusfamilykinase2/Stat5tyrosinephosphorylationandproliferationofBaf3cells.TheaugmentationoftheoppositeeffectsofGM-CSFandIFN-αonTF-1cellgrowthbySodiumstibogluconateindicateitsbroadactivitiesinthesignalingofvariouscytokines.

Details

Established in 2010, located in Hangzhou Qinglan science park, lingruichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals tovarious industries.n our R&D centre. we have a staff of skilled and experienced research chemists. This has enabled us to meet the special reauirements of our customers and it has enabled us to provide quality products at competitive prices.

1. How can we guarantee quality

Always a pre-production sample before mass production;

Always final Inspection before shipment; 

2.What can you buy from us

Plant Extracts,Cosmetics Raw Materials,Vitamin Raw Materials,Pharmaceutical Raw Materials and Intermediates

3. Why should you buy from us not from other suppliers

Our company mainly devoted in producing pharmacetical intermediates , Vitamins , and health supplement , the quality and technical content can reach the advance level in China .Our products are sold well in China as well as in more than 20 countries.

Lingrui's credo is committed to your reliable business partner,reliable quality, competitive prices and superior service, lf you are interested in any of our products or would like to discuss a custom order, please feel free to contact us. We are looking forward to forming successful business relationships with new clients around the world in the near future !