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Country: China (Mainland)
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Tel: 86 571-88092529
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Tel: 86 571-88092529
Fax: 86 571-87334908
URL: http://www.lingruichem.com
Province/state: Zhejiang
City: Hangzhou
Street: 201-B 2# Building Qinglan science park, 321# JinPeng Str. Xihu District Hangzhou City, PR.CHINA
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CAS NO.55268-74-1
Supply lowest price 55268-74-1 Praziquantel factory global trader
praziquantel (praziquantel) is a broad-spectrum anthelmintic synthetic drug discovered abroad in the 70s. after it was reported to be effective against schistosomiasis in 1977, it was trial-produced in China in the same year and proved to have remarkable curative effect on schistosomiasis japonica. this product is colorless crystalline powder, odorless and slightly bitter, and stable under normal conditions. Soluble in chloroform, dimethyl sulfoxide and other organic solvents, slightly soluble in ethanol, insoluble in water. Histochemical observations of in vivo and in vitro tests showed that after the action of the drug, the glycogen of the schistosomiasis was significantly reduced, ribonucleic acid and alkaline phosphatase also decreased, and the activity of alkaline protein reaction or acid phosphatase increased.
praziquantel has a significant effect on killing schistosome adults. Its insecticidal mechanism, from the molecular level, is that praziquantel quickly destroys the Ca2 balance in the insect body. On the one hand, it causes the activity of the worm body to be excited and muscle contracture, so that the schistosomiasis parasitic in the portal system cannot be adsorbed on the blood vessel wall and is brought into the blood stream. The liver (liver migration) is damaged; the second is that the syncytial cortex of schistosomiasis is damaged, in addition to affecting the absorption, excretion and secretion functions of the worm, in addition to the disorder of sugar metabolism and enzyme system, the body surface antigenic determinants of the insect are exposed, and the host's immune system is recognized, attracting a large number of inflammatory cells such as neutrophils, eosinophils, macrophages and other aggregates around the insect body to attack.
Established in 2010, located in Hangzhou Qinglan science park, lingruichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals tovarious industries.n our R&D centre. we have a staff of skilled and experienced research chemists. This has enabled us to meet the special reauirements of our customers and it has enabled us to provide quality products at competitive prices.
1. How can we guarantee quality
Always a pre-production sample before mass production;
Always final Inspection before shipment;
2.What can you buy from us
Plant Extracts,Cosmetics Raw Materials,Vitamin Raw Materials,Pharmaceutical Raw Materials and Intermediates
3. Why should you buy from us not from other suppliers
Our company mainly devoted in producing pharmacetical intermediates , Vitamins , and health supplement , the quality and technical content can reach the advance level in China .Our products are sold well in China as well as in more than 20 countries.
Lingrui's credo is committed to your reliable business partner,reliable quality, competitive prices and superior service, lf you are interested in any of our products or would like to discuss a custom order, please feel free to contact us. We are looking forward to forming successful business relationships with new clients around the world in the near future !