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CAS NO.138-59-0
Hot selling 138-59-0 Best price Shikimic acid in China
shikimic acid is a water-soluble white crystalline powder. It was first isolated from Japanese shikima and named, is an important metabolite of plants and microorganisms. For a long time, shikimic acid is mainly extracted from dried and mature fruits of star anise or Japanese shikimia (Japanese anise), in recent years, studies on the extraction of shikimic acid from the fruits of North American liquidambar and pine needles have also been reported.
shikimic acid is present in the dried mature fruit of the Magnoliaceae plant. Star anise is a kind of evergreen tree grown in a humid, warm and semi-yin environment, high to 30 meters. Mainly distributed in Fujian, Guangdong, Guangxi, Yunnan, Guizhou and other provinces in the mountain soil. The bark was gray to red-brown in color. The whole margin was single-lobed, grown in the shape of a needle, the leaves were leathery, short-stem, 6-12cm in length and 2-5cm in width, with transparent oil spots on the upper surface. Flowering in spring and autumn. The flowers were single in the axilla of the leaf. There are 3 yellow-green sepals; 6-9 flowers, pink to deep red. Autumn to spring of the second year. The aggregate fruit is star-shaped, octagonal, 1-2cm long, 3-5cm wide, <1cm high. Mature from green to yellow. Mango tips are blunt or blunt-pointed, each containing one seed 6mm long. The fruits are picked in autumn and winter and are red-brown or yellow-brown after drying. The smell is aromatic and sweet. Shikimia, also known as Wild star anise, is a shrub, Evergreen, the seeds are light brown, shiny, flowering 5 months, the fruit period from 9 to 10 months, mainly distributed in the less than 1200 in the desert slope of the forest, autumn results, the fruit contains a large amount of shikimic acid, the fruit is very similar to the anise, but toxic, should avoid confusion.
shikimic acid is a key feedstock for the production of Tamiflu by Roche. Shikimic acid, which is currently used in Roche, is processed and extracted from anise. The steps of synthesizing shikimic acid from petrochemical raw materials are complex, and there is no production and application value except scientific research at present. Shikimic acid can be synthesized from another natural product, quinic acid, which requires several steps of reaction. Quinic acid is derived from the bark of cinchona tree and can be extracted and supplied in large quantities like shikimic acid. The origin of the cinchona tree is mainly in the African country Zaire, but due to the political instability in ZRA, it is difficult to commercially ensure the supply of cinchona bark. At present, another method for producing shikimic acid is to use the method of biological fermentation, and glucose is used as the raw material. This is the second production scheme prepared by Roche in the production of Tamiflu to prevent the instability of the source of star anise (shikimic acid). Roche's fermentation method shikimic acid is produced in northern Europe. The production of shikimic acid by fermentation has been stopped due to the loss of high production costs. Roche claims that 1/3 of its shikimic acid used in Tamiflu production comes from fermentation.
Established in 2010, located in Hangzhou Qinglan science park, lingruichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals tovarious industries.n our R&D centre. we have a staff of skilled and experienced research chemists. This has enabled us to meet the special reauirements of our customers and it has enabled us to provide quality products at competitive prices.
1. How can we guarantee quality
Always a pre-production sample before mass production;
Always final Inspection before shipment;
2.What can you buy from us
Plant Extracts,Cosmetics Raw Materials,Vitamin Raw Materials,Pharmaceutical Raw Materials and Intermediates
3. Why should you buy from us not from other suppliers
Our company mainly devoted in producing pharmacetical intermediates , Vitamins , and health supplement , the quality and technical content can reach the advance level in China .Our products are sold well in China as well as in more than 20 countries.
Lingrui's credo is committed to your reliable business partner,reliable quality, competitive prices and superior service, lf you are interested in any of our products or would like to discuss a custom order, please feel free to contact us. We are looking forward to forming successful business relationships with new clients around the world in the near future !