Keywords

• low price 156545-07-2
• Buy 156545-07-2 in China
• 3,5-Difluorophenylboronic acid good supplier

Quick Details

• ProName: low price 156545-07-2 Buy 3,5-Difluoro...
• CasNo: 156545-07-2
• Molecular Formula: C6H5BF2O2
• Appearance: Crystalline powder
• Application: Organic synthesis and pharmaceutical a...
• DeliveryTime: Stocks
• PackAge: according to customers' requirements
• Port: Any port
• ProductionCapacity: 100 Metric Ton/Day
• Purity: 99%
• Storage: Keep in dark place,Sealed in dry,Room ...
• Transportation: By air(EMS or EUB or FedEx or TNT ect....
• LimitNum: 1 Gram

Superiority

low price 156545-07-2 Buy 3,5-Difluorophenylboronic acid  in China

3, 5-difluorophenylboronic acid is a fluorophenylboronic acid, which is a yellow solid. Fluorophenylboronic acid is a kind of organic synthesis and pharmaceutical and chemical intermediates that are relatively stable in the air, insensitive to moisture, can be stored for a long time and have high reactivity. The Suzuki coupling reaction of fluorophenylboronic acid and halogenated aromatic hydrocarbons has good position selectivity and stereoselectivity. Various chemical functional groups do not change in the reaction. The reaction conditions are mild and the yield is high. It is an important way to form C- C bonds.

5L three-mouth bottle with 62g(2.6mol) of magnesium chips and 750ml of tetrahydrofuran, a spherical condenser tube with a drying tube and a dropping funnel, 482.5g(2.5mol) of 3,5-difluorobromobenzene and 1500ml of tetrahydrofuran (confirming the reaction initiation) dropwise, add heat and reflux for 0.5 hours after adding, and keep positive pressure with nitrogen, stir, cool to -50 ℃ in a low-temperature bath, add 850g(3.7mol)-500ml tetrahydrofuran solution dropwise, when the reaction solution is lower than -50 ℃, use about 1.5 hours, stir in the bath for 5 minutes after adding, then stir to room temperature, leave overnight, add 500ml concentrated hydrochloric acid (analytically pure, the same below)-1000ml water for hydrolysis, stir for 1 hour; then add 2L of ethyl acetate, separate the liquid, saturated salt water wash to neutral; water bath decompression steam solvent, cooling to room temperature, suction filtration, 3, 5-difluorophenylboronic acid. Yield: 296g (75% of theoretical value), melting point: 210 ℃.

Details

Established in 2010, located in Hangzhou Qinglan science park, lingruichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals tovarious industries.n our R&D centre. we have a staff of skilled and experienced research chemists. This has enabled us to meet the special reauirements of our customers and it has enabled us to provide quality products at competitive prices.

1. How can we guarantee quality

Always a pre-production sample before mass production;

Always final Inspection before shipment; 

2.What can you buy from us

Plant Extracts,Cosmetics Raw Materials,Vitamin Raw Materials,Pharmaceutical Raw Materials and Intermediates

3. Why should you buy from us not from other suppliers

Our company mainly devoted in producing pharmacetical intermediates , Vitamins , and health supplement , the quality and technical content can reach the advance level in China .Our products are sold well in China as well as in more than 20 countries.

Lingrui's credo is committed to your reliable business partner,reliable quality, competitive prices and superior service, lf you are interested in any of our products or would like to discuss a custom order, please feel free to contact us. We are looking forward to forming successful business relationships with new clients around the world in the near future !